Peptides are chemical compounds with more than two amino acids joined together using a peptide bond. This bond is said to be a special linkage where nitrogen atom of a single amino acid joins the carboxyl carbon atom or particle of another. Today you can research peptides online by visiting the websites that offer these products.
Peptides are categorized according to the amino acid residues number. Oligopeptides have less than 10 amino acids. Protein on the other hand is used to describe molecules containing over 50 amino acids.
Molecules that have numerous molecular weights are said to polypeptides while the terms protein and polypeptide can be used interchangeably.
Emil Fischer is the one who first discovered synthetic peptide in 1901. He featured Ernest Foumeauin his work of study. The first polypeptide was synthesized in 1953by none other than Vincent du Vigneaud.
Peptides however can be applied in many occasions especially in biotechnology and medicine. They control most physiological processes. They act as paracrine or endocrine signals at some sites. They also act as growth factors or neurotransmitters to other sites.
Did you know that insulin is believed first therapeutic protein used in the treatment of insulin-dependent diabetes? This was in the 1920s according to researches. About sixty FDA peptide drugs can get them in the market. Approximately 140 peptide drugs are still in clinical trials not forgetting that other 500 more are said to be in pre-clinical development.
The main function of C-peptide is to determine the main cause of hypoglycemia as well as monitoring the production of insulin. For children, igf-1 plays a major role in growth. Igf-1 has 70 amino acids and a molecular weight of 7,649(D)
Peptides are produced by joining the C-terminus or carboxyl group of a single amino acid to N-terminus or amino group of another. Remember there are two main strategies used in the peptide synthesis. These are solid-phase peptide synthesis and liquid-phase peptide synthesis.